Causes of Vitamin K2 Deficiency

Written by Vitatree | Jun 12, 2025 8:12:12 PM

Introduction

Vitamin K2 is essential for bone health, cardiovascular function, and calcium metabolism. Yet, many people unknowingly suffer from a deficiency. Here are six common causes of low vitamin K2 levels.

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1. Insufficient Dietary Intake

Many of us simply aren't eating enough foods rich in vitamin K2. This is especially true for those on vegetarian or plant-based diets, as the highest sources of K2 are typically animal-based or fermented foods. In Western diets—such as the standard American diet—we tend to lack foods like natto (fermented soybeans), which are high in K2 and more common in other parts of the world.

2. Poor Absorption

As we age, our digestive enzymes naturally decline. This reduced enzyme activity can impair our ability to absorb nutrients, including fat-soluble vitamins like K2. Even if your diet includes some K2, poor absorption could still lead to a deficiency.

3. Disruptions in Gut Bacteria

Your gut microbiome plays a critical role in synthesizing and absorbing vitamin K2. An imbalance—too many harmful bacteria and not enough beneficial ones—can interfere with nutrient production and absorption, contributing to a deficiency.

4. Conditions Affecting Fat Absorption

Vitamin K2 is a fat-soluble vitamin, which means proper fat digestion is crucial for its absorption. If your liver or gallbladder isn’t functioning optimally, it could impair fat absorption—and with it, your ability to utilize vitamin K2. Conditions like gallstones, bile insufficiency, or liver disease can all play a role.

5. Antibiotic Use

While antibiotics are sometimes necessary, they can also disrupt your gut flora, wiping out the good bacteria that help produce and support the absorption of vitamin K2. Frequent or long-term antibiotic use is a common factor in deficiencies.

6. Certain Medications

Several medications can interfere with vitamin K2 levels, including:

Acid Reflux medications (PPIs)
Anti-seizure drugs
Certain treatments for chronic illnesses

These drugs may hinder absorption or disrupt gut bacteria, both of which reduce K2 levels in the body.

REFERENCE: J9CON230271

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