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Top 3 Supplements You Should NEVER Take with Coffee

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Brewing a morning cup of joe is a daily ritual for many people around the world. But if you take certain supplements with your coffee, research shows certain vitamins & minerals could be flushed more quickly through your system & how absorption could be compromised by taking them with coffee. In fact, there are three specific supplements that you should never take with coffee.

How Caffeine Works?

Caffeine is a natural stimulant found in coffee. When consumed, caffeine is absorbed from the stomach into the bloodstream and binds to the adenosine receptors of the brain. This blocks the action of adenosine, a neurotransmitter that is involved in alertness and fatigue. As a result, caffeine increases alertness, focus, and energy levels. However, caffeine can also interfere with the absorption and efficacy of certain medications and supplements. This is because it increases the rate of elimination of certain compounds. Thus, certain supplements should not be taken with coffee as they could be flushed out of the body more quickly.

Caffeine & supplements

While caffeine can increase the rate at which some supplements and medications are eliminated from the body, it can also lead to reduced absorption. This is because caffeine can interfere with the absorption of certain vitamins and minerals in the digestive tract. As a result, taking supplements with coffee can affect their absorption and make them significantly less effective. When taken with coffee, absorption of certain vitamin & minerals could decrease, potentially making them less effective.


3 Supplements You Should NEVER Take with Coffee

1. Vitamin D

  • Taking vitamin D with coffee can decrease its absorption. Studies have shown that coffee interferes with the absorption of vitamin D. The best way to get your daily dose of Vitamin D is through natural sunlight – but if you take a vitamin D supplement, do not take it at the same time as your coffee, as it might limit the amount of Vitamin D that's absorbed by your body. Therefore, it is best to take vitamin D supplements at least 1 hour before or after coffee.

2. B vitamins

  • When it comes to B vitamins and coffee, we highly recommend you never mix the two. Coffee is a natural diuretic that speeds up our body's fluid flushing process. If you take your B vitamins while drinking coffee, they're likely going to be rendered less effective as they quickly pass through our system. So if you are taking a multivitamin or an individual B vitamin, like vitamin B12, avoid taking them with a cup of coffee.

3. Magnesium

  • Magnesium is a vital mineral that plays an important role in our body, especially for energy production. Though we can get magnesium from our diet, many people supplement this important mineral. So it's important to take it at the right time and in the right way. Mixing magnesium and coffee can interfere with the body's absorption of magnesium. If you take a magnesium supplement, it's best to avoid taking it within an hour before or after drinking coffee.


In conclusion, if you take any of the following supplements, it’s best to avoid mixing them with coffee. Vitamin D, B vitamins, and magnesium can all be affected by caffeine intake, which can mean that your body flushes them more quickly or their absorption is reduced. Therefore, you should always make sure to have a gap between drinking coffee and taking these three supplements- at least an hour should suffice. Get the full benefit from your supplements!
3 Supplements NOT to take with Coffee

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